Pausing as a mechanism of nucleosome recovery
نویسندگان
چکیده
منابع مشابه
A positioned +1 nucleosome enhances promoter-proximal pausing
Chromatin distribution is not uniform along the human genome. In most genes there is a promoter-associated nucleosome free region (NFR) followed by an array of nucleosomes towards the gene body in which the first (+1) nucleosome is strongly positioned. The function of this characteristic chromatin distribution in transcription is not fully understood. Here we show in vivo that the +1 nucleosome...
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15 صفحه اولMechanism of sequence-specific pausing of bacterial RNA polymerase.
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The multisubunit RNAPs (RNA polymerases) found in all cellular life forms are remarkably conserved in fundamental structure, in mechanism and in their susceptibility to sequence-dependent pausing during transcription of DNA in the absence of elongation regulators. Recent studies of both prokaryotic and eukaryotic transcription have yielded an increasing appreciation of the extent to which gene ...
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ژورنال
عنوان ژورنال: Epigenetics & Chromatin
سال: 2013
ISSN: 1756-8935
DOI: 10.1186/1756-8935-6-s1-p14